Case Report: Co-Existence of BRCA2 and PALB2 Germline Mutations in Familial Prostate Cancer With Solitary Lung Metastasis

BACKGROUND: Mutation-caused loss-of-function of factors involved in DNA damage response (DDR) is responsible for the development and progression of ~20% of prostate cancer (PCa). Some mutations can be used in cancer risk assessment and informed treatment decisions. METHODS: Target capture-based deep...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Tang, Tang, Wang, Lin-ang, Wang, Peng, Tong, Dali, Liu, Gaolei, Zhang, Jun, Dai, Nan, Zhang, Yao, Yuan, Gang, Geary, Kyla, Zhang, Dianzheng, Liu, Qiuli, Jiang, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649358/
https://ncbi.nlm.nih.gov/pubmed/33194641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.564694
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