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Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNA
Von Willebrand disease (VWD) is the most common inherited bleeding disorder and is mainly caused by dominant-negative mutations in the multimeric protein von Willebrand factor (VWF). These mutations may either result in quantitative or qualitative defects in VWF. VWF is an endothelial protein that i...
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| Publicado no: | Thromb Haemost |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Georg Thieme Verlag KG
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7649061/ https://ncbi.nlm.nih.gov/pubmed/32803740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1715442 |
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