Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease

Several missense mutations in the von Willebrand Factor (VWF) gene of von Willebrand disease (VWD) patients have been shown to cause impaired constitutive secretion and intracellular retention of VWF. However, the effects of those mutations on the intracellular storage in Weibel-Palade bodies (WPBs)...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Jiong-Wei, Valentijn, Karine M., de Boer, Hetty C., Dirven, Richard J., van Zonneveld, Anton Jan, Koster, Abraham J., Voorberg, Jan, Reitsma, Pieter H., Eikenboom, Jeroen
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129199/
https://ncbi.nlm.nih.gov/pubmed/21596755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215194
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires