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Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease
Several missense mutations in the von Willebrand Factor (VWF) gene of von Willebrand disease (VWD) patients have been shown to cause impaired constitutive secretion and intracellular retention of VWF. However, the effects of those mutations on the intracellular storage in Weibel-Palade bodies (WPBs)...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129199/ https://ncbi.nlm.nih.gov/pubmed/21596755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215194 |
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