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In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells

This study aims at merging the therapeutic effects associated to the inhibition of Carbonic Anhydrase IX (CAIX), an essential enzyme overexpressed by cancer cells including mesothelioma and breast cancer, with those ones brought by the application of Boron Neutron Capture Therapy (BNCT). This task w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alberti, Diego, Michelotti, Alessia, Lanfranco, Alberto, Protti, Nicoletta, Altieri, Saverio, Deagostino, Annamaria, Geninatti Crich, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648750/
https://ncbi.nlm.nih.gov/pubmed/33159147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76370-1
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