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In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells

This study aims at merging the therapeutic effects associated to the inhibition of Carbonic Anhydrase IX (CAIX), an essential enzyme overexpressed by cancer cells including mesothelioma and breast cancer, with those ones brought by the application of Boron Neutron Capture Therapy (BNCT). This task w...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Alberti, Diego, Michelotti, Alessia, Lanfranco, Alberto, Protti, Nicoletta, Altieri, Saverio, Deagostino, Annamaria, Geninatti Crich, Simonetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648750/
https://ncbi.nlm.nih.gov/pubmed/33159147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76370-1
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