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Functional redundancy of Burkholderia pseudomallei phospholipase C enzymes and their role in virulence

Phospholipase C (PLC) enzymes are key virulence factors in several pathogenic bacteria. Burkholderia pseudomallei, the causative agent of melioidosis, possesses at least three plc genes (plc1, plc2 and plc3). We found that in culture medium plc1 gene expression increased with increasing pH, whilst e...

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Publicado en:Sci Rep
Main Authors: Srinon, Varintip, Withatanung, Patoo, Chaiwattanarungruengpaisan, Somjit, Thongdee, Metawee, Meethai, Chatruthai, Stevens, Joanne M., Titball, Richard W., Korbsrisate, Sunee
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648637/
https://ncbi.nlm.nih.gov/pubmed/33159122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76186-z
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