Functional redundancy of Burkholderia pseudomallei phospholipase C enzymes and their role in virulence

Phospholipase C (PLC) enzymes are key virulence factors in several pathogenic bacteria. Burkholderia pseudomallei, the causative agent of melioidosis, possesses at least three plc genes (plc1, plc2 and plc3). We found that in culture medium plc1 gene expression increased with increasing pH, whilst e...

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Vydáno v:Sci Rep
Hlavní autoři: Srinon, Varintip, Withatanung, Patoo, Chaiwattanarungruengpaisan, Somjit, Thongdee, Metawee, Meethai, Chatruthai, Stevens, Joanne M., Titball, Richard W., Korbsrisate, Sunee
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648637/
https://ncbi.nlm.nih.gov/pubmed/33159122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76186-z
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