Besifloxacin liposomes with positively charged additives for an improved topical ocular delivery

Topical ophthalmic antibiotics show low efficacy due to the well-known physiological defense mechanisms of the eye, which prevents the penetration of exogenous substances. Here, we aimed to incorporate besifloxacin into liposomes containing amines as positively charged additives and to evaluate the...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: dos Santos, Giselly Almeida, Ferreira-Nunes, Ricardo, Dalmolin, Luciana Facco, dos Santos Ré, Ana Carolina, Anjos, Jorge Luiz Vieira, Mendanha, Sebastião Antônio, Aires, Carolina Patrícia, Lopez, Renata F. V., Cunha-Filho, Marcilio, Gelfuso, Guilherme M., Gratieri, Taís
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648625/
https://ncbi.nlm.nih.gov/pubmed/33159142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76381-y
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