Besifloxacin liposomes with positively charged additives for an improved topical ocular delivery

Topical ophthalmic antibiotics show low efficacy due to the well-known physiological defense mechanisms of the eye, which prevents the penetration of exogenous substances. Here, we aimed to incorporate besifloxacin into liposomes containing amines as positively charged additives and to evaluate the...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: dos Santos, Giselly Almeida, Ferreira-Nunes, Ricardo, Dalmolin, Luciana Facco, dos Santos Ré, Ana Carolina, Anjos, Jorge Luiz Vieira, Mendanha, Sebastião Antônio, Aires, Carolina Patrícia, Lopez, Renata F. V., Cunha-Filho, Marcilio, Gelfuso, Guilherme M., Gratieri, Taís
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648625/
https://ncbi.nlm.nih.gov/pubmed/33159142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76381-y
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