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UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest

Translation arrest is a part of the cellular stress response that decreases energy consumption and enables rapid reprioritisation of gene expression. Often translation arrest leads to condensation of untranslated messenger ribonucleoproteins (mRNPs) into stress granules (SGs). Studies into mechanism...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Ying, Shan, Khaperskyy, Denys A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648617/
https://ncbi.nlm.nih.gov/pubmed/32989041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248310
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