Interleukin-34 Limits the Therapeutic Effects of Immune Checkpoint Blockade

Interleukin-34 (IL-34) is an alternative ligand to colony-stimulating factor-1 (CSF-1) for the CSF-1 receptor that acts as a key regulator of monocyte/macrophage lineage. In this study, we show that tumor-derived IL-34 mediates resistance to immune checkpoint blockade regardless of CSF-1 existence i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:iScience
Main Authors: Hama, Naoki, Kobayashi, Takuto, Han, Nanumi, Kitagawa, Fumihito, Kajihara, Nabeel, Otsuka, Ryo, Wada, Haruka, Lee, Hee-kyung, Rhee, Hwanseok, Hasegawa, Yoshinori, Yagita, Hideo, Baghdadi, Muhammad, Seino, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648133/
https://ncbi.nlm.nih.gov/pubmed/33205010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101584
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados