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Icariin‐induced inhibition of SIRT6/NF‐κB triggers redox mediated apoptosis and enhances anti‐tumor immunity in triple‐negative breast cancer

Abnormal activation of the nuclear factor‐kappa B (NF‐κB) signaling pathway is closely implicated in triple‐negative breast cancer growth, metastasis, and tumor immune escape. In this study, the anti‐cancer effects of icariin, a natural flavonol glycoside, toward breast cancer cells and the underlyi...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Song, Linjiang, Chen, Xian, Mi, Ling, Liu, Chi, Zhu, Shaomi, Yang, Tianlin, Luo, Xiaohong, Zhang, Qinxiu, Lu, Hua, Liang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648025/
https://ncbi.nlm.nih.gov/pubmed/32926492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14648
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