Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes

Osteoarthritis (OA) is a common chronic and degenerative joint condition that is mainly characterized by cartilage degradation, osteophyte formation, and joint stiffness. The NF-κB signaling pathway in inflammation, autophagy, and apoptosis plays a prominent role in the progression of OA. Icariin, a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Mi, Bobin, Wang, Junqing, Liu, Yi, Liu, Jing, Hu, Liangcong, Panayi, Adriana C., Liu, Guohui, Zhou, Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008570/
https://ncbi.nlm.nih.gov/pubmed/29950992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00605
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