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Targeted Delivery of Cell Softening Micelles to Schlemm’s Canal Endothelial Cells for Treatment of Glaucoma

Increased stiffness of the Schlemm’s canal (SC) endothelium in the aqueous humor outflow pathways has been associated with elevated intraocular pressure (IOP) in glaucoma. Novel treatments that relax this endothelium, such as actin depolymerizers and rho kinase inhibitors, are in development. Unfort...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Stack, Trevor, Vincent, Michael, Vahabikashi, Amir, Li, Guorong, Perkumas, Kristin M., Stamer, W. Daniel, Johnson, Mark, Scott, Evan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647937/
https://ncbi.nlm.nih.gov/pubmed/33015961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.202004205
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