Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma

Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior of Schlemm’s canal (SC) cells contributes to this dysfunction. We used atomi...

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Detalhes bibliográficos
Main Authors: Overby, Darryl R., Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf, Braakman, Sietse T., Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J., Johnson, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183270/
https://ncbi.nlm.nih.gov/pubmed/25201985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410602111
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