Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma

Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior of Schlemm’s canal (SC) cells contributes to this dysfunction. We used atomi...

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Hauptverfasser: Overby, Darryl R., Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf, Braakman, Sietse T., Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J., Johnson, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183270/
https://ncbi.nlm.nih.gov/pubmed/25201985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410602111
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