Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma

Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior of Schlemm’s canal (SC) cells contributes to this dysfunction. We used atomi...

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Autors principals: Overby, Darryl R., Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf, Braakman, Sietse T., Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J., Johnson, Mark
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183270/
https://ncbi.nlm.nih.gov/pubmed/25201985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410602111
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