p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

The tumor suppressor p53 as an innate antiviral regulator contributes to restricting Japanese encephalitis virus (JEV) replication, but the mechanism is still unclear. The interferon-induced transmembrane protein 3 (IFITM3) is an intrinsic barrier to a range of virus infection, whether IFITM3 is res...

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Pubblicato in:PLoS Pathog
Autori principali: Wang, Xin, Wu, Zhuanchang, Li, Yuming, Yang, Yifan, Xiao, Changguang, Liu, Xiqian, Xiang, Xiao, Wei, Jianchao, Shao, Donghua, Liu, Ke, Deng, Xufang, Wu, Jiaqiang, Qiu, Yafeng, Li, Beibei, Ma, Zhiyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647115/
https://ncbi.nlm.nih.gov/pubmed/33108395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009035
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