Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription

Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS, which has important impacts on the pig industry. PRRSV infection results in disruption of the swine leukocyte antigen class I (SLA-I) antigen presentation pathway. In this study, highly pathogenic PRRSV (HP-P...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Qi, Pengfei, Liu, Ke, Wei, Jianchao, Li, Yuming, Li, Beibei, Shao, Donghua, Wu, Zhuanchang, Shi, Yuanyuan, Tong, Guangzhi, Qiu, Yafeng, Ma, Zhiyong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309937/
https://ncbi.nlm.nih.gov/pubmed/28003480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01755-16
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