Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient-derived organoids

Enhancing the radioresponsiveness of colorectal cancer (CRC) is essential for local control and prognosis. However, consequent damage to surrounding healthy cells can lead to treatment failure. We hypothesized that short-chain fatty acids (SCFAs) could act as radiosensitizers for cancer cells, allow...

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Veröffentlicht in:Int J Oncol
Hauptverfasser: Park, Misun, Kwon, Junhye, Shin, Hye-Jin, Moon, Sun Mi, Kim, Sang Bum, Shin, Ui Sup, Han, Young-Hoon, Kim, Younjoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646587/
https://ncbi.nlm.nih.gov/pubmed/33173975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2020.5132
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