Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient-derived organoids

Enhancing the radioresponsiveness of colorectal cancer (CRC) is essential for local control and prognosis. However, consequent damage to surrounding healthy cells can lead to treatment failure. We hypothesized that short-chain fatty acids (SCFAs) could act as radiosensitizers for cancer cells, allow...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Oncol
Prif Awduron: Park, Misun, Kwon, Junhye, Shin, Hye-Jin, Moon, Sun Mi, Kim, Sang Bum, Shin, Ui Sup, Han, Young-Hoon, Kim, Younjoo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2020
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646587/
https://ncbi.nlm.nih.gov/pubmed/33173975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2020.5132
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