Gemcitabine and Selected mTOR Inhibitors in Uterine Sarcomas and Carcinosarcoma Cells- an Isobolographic Analysis

Introduction: mTOR inhibitors are anticancer agents affecting mTOR/AKT/PI3K pathway that is one of the most important in human cancer cells. Hyperactivation of mTOR/AKT/PI3K and overexpression of this pathway members are frequently reported in uterine sarcoma and carcinosarcoma. Present study is aim...

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Détails bibliographiques
Publié dans:Int J Med Sci
Auteurs principaux: Bobiński, Marcin, Okła, Karolina, Łuszczki, Jarogniew, Bednarek, Wiesława, Wawruszak, Anna, Moreno-Bueno, Gema, Garcia-Sanz, Pablo, Dmoszyńska-Graniczka, Magdalena, Tarkowski, Rafał, Kotarski, Jan
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646097/
https://ncbi.nlm.nih.gov/pubmed/33173419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.48187
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