Accumulation of blood-circulating PD-L1-expressing M-MDSCs and monocytes/macrophages in pretreatment ovarian cancer patients is associated with soluble PD-L1

BACKGROUND: Previous studies have shown clinical relevance of programmed death-ligand 1 (PD-L1) and soluble PD-L1 (sPD-L1) in human cancers. However, still contradictory results exist. Our aim was evaluation of PD-L1-expressing monocytic myeloid-derived suppressor cells (M-MDSCs), monocytes/macropha...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Okła, Karolina, Rajtak, Alicja, Czerwonka, Arkadiusz, Bobiński, Marcin, Wawruszak, Anna, Tarkowski, Rafał, Bednarek, Wiesława, Szumiło, Justyna, Kotarski, Jan
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268341/
https://ncbi.nlm.nih.gov/pubmed/32487171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02389-7
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