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Autofluorescence-based sorting removes senescent cells from mesenchymal stromal cell cultures

Mesenchymal stromal cells (MSC) are used in cell therapy, but results depend on the unknown quality of cell populations. Extended culture time of MSC increases their senescent levels, leading to a critical loss of cell fitness. Here, we tested the suitability of MSC-sorting based on their FACS autof...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Bertolo, Alessandro, Guerrero, Julien, Stoyanov, Jivko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645702/
https://ncbi.nlm.nih.gov/pubmed/33154552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76202-2
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