Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function

Human iPS cell (iPSC)-derived cardiomyocytes (CMs) hold promise for drug discovery for heart diseases and cardiac toxicity tests. To utilize human iPSC-derived CMs, the establishment of three-dimensional (3D) heart tissues from iPSC-derived CMs and other heart cells, and a sensitive bioassay system...

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Vydáno v:Sci Rep
Hlavní autoři: Abulaiti, Mosha, Yalikun, Yaxiaer, Murata, Kozue, Sato, Asako, Sami, Mustafa M., Sasaki, Yuko, Fujiwara, Yasue, Minatoya, Kenji, Shiba, Yuji, Tanaka, Yo, Masumoto, Hidetoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645446/
https://ncbi.nlm.nih.gov/pubmed/33154509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76062-w
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