Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease

Cholesterol‐dependent cytolysins (CDCs) are essential virulence factors for many human pathogens like Streptococcus pneumoniae (pneumolysin, PLY), Streptococcus pyogenes (streptolysin O, SLO), and Listeria monocytogenes (Listeriolysin, LLO) and induce cytolysis and inflammation. Recently, we identif...

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Pubblicato in:EMBO Mol Med
Autori principali: Subramanian, Karthik, Iovino, Federico, Tsikourkitoudi, Vasiliki, Merkl, Padryk, Ahmed, Sultan, Berry, Samuel B, Aschtgen, Marie‐Stephanie, Svensson, Mattias, Bergman, Peter, Sotiriou, Georgios A, Henriques‐Normark, Birgitta
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645366/
https://ncbi.nlm.nih.gov/pubmed/32985105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012695
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