Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease

Cholesterol‐dependent cytolysins (CDCs) are essential virulence factors for many human pathogens like Streptococcus pneumoniae (pneumolysin, PLY), Streptococcus pyogenes (streptolysin O, SLO), and Listeria monocytogenes (Listeriolysin, LLO) and induce cytolysis and inflammation. Recently, we identif...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Subramanian, Karthik, Iovino, Federico, Tsikourkitoudi, Vasiliki, Merkl, Padryk, Ahmed, Sultan, Berry, Samuel B, Aschtgen, Marie‐Stephanie, Svensson, Mattias, Bergman, Peter, Sotiriou, Georgios A, Henriques‐Normark, Birgitta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645366/
https://ncbi.nlm.nih.gov/pubmed/32985105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012695
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