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Klotho deficiency aggravates diabetes-induced podocyte injury due to DNA damage caused by mitochondrial dysfunction

Diabetic nephropathy (DN) is a progressive disease, the main pathogeny of which is podocyte injury inducing glomerular filtration barrier and proteinuria. The occurrence and development of DN could be partly attributed to the reactive oxygen species (ROS) generated by mitochondria. However, research...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Chen, Zhi, Zhou, Qing, Liu, Cong, Zeng, Yiping, Yuan, Shaolong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645346/
https://ncbi.nlm.nih.gov/pubmed/33162804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.49690
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