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Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice

Objective: Uncoupling protein 2 (UCP2) is a member of inner mitochondrial membrane proteins and deletion of UCP2 exacerbates brain damage after cerebral ischemia/reperfusion (I/R). Nevertheless, its functional role during cerebral I/R is not entirely understood. The objective of present study was to...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Med Sci
Hauptverfasser: He, Maotao, Zhang, Ting, Fan, Yucheng, Ma, Yanmei, Zhang, Jianzhong, Jing, Li, Li, P. Andy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645345/
https://ncbi.nlm.nih.gov/pubmed/33162815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.49849
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