The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese

Objective: A novel functional cis-regulatory element (CRE) located at SNCA intron 4 has recently been identified in association with Parkinson’s disease (PD) risk in European descendants. We aimed to investigate whether this CRE is associated with PD in Han Chinese ethnicity. Methods: A Chinese coho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Genet
Prif Awduron: Zhu, Shi-Guo, Lu, Hui, Mao, Miao, Li, Zhao-Feng, Cui, Lei, Ovlyakulov, Begench, Zhang, Xiong, Zhu, Jian-Hong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Genetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645113/
https://ncbi.nlm.nih.gov/pubmed/33193729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.590365
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