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Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis

Intestinal epithelial barrier is critical for the maintenance of normal gut homeostasis and disruption of this barrier may trigger or exaggerate mucosal inflammation. The actin cytoskeleton is a key regulator of barrier structure and function, controlling the assembly and permeability of epithelial...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Lechuga, Susana, Naydenov, Nayden G., Feygin, Alex, Cruise, Michael, Ervasti, James M., Ivanov, Andrei I.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644907/
https://ncbi.nlm.nih.gov/pubmed/33195251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.588836
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