African Vegetables (Clerodendrum volubile Leaf and Irvingia gabonensis Seed Extracts) Effectively Mitigate Trastuzumab-Induced Cardiotoxicity in Wistar Rats

Trastuzumab (TZM) is a humanized monoclonal antibody that has been approved for the clinical management of HER2-positive metastatic breast and gastric cancers but its use is limited by its cumulative dose and off-target cardiotoxicity. Unfortunately, till date, there is no approved antidote to this...

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Publicat a:Oxid Med Cell Longev
Autors principals: Olorundare, Olufunke, Adeneye, Adejuwon, Akinsola, Akinyele, Soyemi, Sunday, Mgbehoma, Alban, Okoye, Ikechukwu, Ntambi, James M., Mukhtar, Hasan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644299/
https://ncbi.nlm.nih.gov/pubmed/33178389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9535426
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