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Growth hormone signaling pathways
Over 20 years ago, our laboratory showed that growth hormone (GH) signals through the GH receptor-associated tyrosine kinase JAK2. We showed that GH binding to its membrane-bound receptor enhances binding of JAK2 to the GHR, activates JAK2, and stimulates tyrosyl phosphorylation of both JAK2 and GHR...
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| Published in: | Growth Horm IGF Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644140/ https://ncbi.nlm.nih.gov/pubmed/26421979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2015.09.002 |
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