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Phosphorylation of the adaptor protein SH2B1β regulates its ability to enhance growth hormone-dependent macrophage motility

Previous studies have shown that growth hormone (GH) recruits the adapter protein SH2B1β to the GH-activated, GH receptor-associated tyrosine kinase JAK2, implicating SH2B1β in GH-dependent actin cytoskeleton remodeling, and suggesting that phosphorylation at serines 161 and 165 in SH2B1β releases S...

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Detalhes bibliográficos
Main Authors: Su, Hsiao-Wen, Lanning, Nathan J., Morris, David L., Argetsinger, Lawrence S., Lumeng, Carey N., Carter-Su, Christin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678408/
https://ncbi.nlm.nih.gov/pubmed/23444381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.113050
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