Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for “polygenic epistasis”

BACKGROUND: The majority of quantitative genetic models used to map complex traits assume that alleles have similar effects across all individuals. Significant evidence suggests, however, that epistatic interactions modulate the impact of many alleles. Nevertheless, identifying epistatic interaction...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Rau, Christoph D., Gonzales, Natalia M., Bloom, Joshua S., Park, Danny, Ayroles, Julien, Palmer, Abraham A., Lusis, Aldons J., Zaitlen, Noah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644088/
https://ncbi.nlm.nih.gov/pubmed/33104702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009165
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