Intra‐CSF topotecan in treatment of breast cancer patients with leptomeningeal metastases

BACKGROUND: There are few treatment options for patients with leptomeningeal metastases (LM). METHODS: We report a case series of patients with breast cancer and LM treated with intra‐CSF topotecan (TOPO). Outcome was assessed by clinical exam and MRI at baseline, at end of induction (4‐5 weeks), th...

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Vydáno v:Cancer Med
Hlavní autoři: Jaeckle, Kurt A., Dixon, Jesse G., Anderson, Stephen Keith, Moreno‐Aspitia, Alvaro, Colon‐Otero, Gerardo, Hebenstreit, Kathy, Patel, Tejal A., Reddy, Samarth L., Perez, Edith A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Clinical Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643683/
https://ncbi.nlm.nih.gov/pubmed/32885617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3422
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