Radiation therapy and secondary malignancy in Li‐Fraumeni syndrome: A hereditary cancer registry study

BACKGROUND: Li‐Fraumeni Syndrome (LFS) is a rare cancer‐predisposing condition caused by germline mutations in TP53. Conventional wisdom and prior work has implied an increased risk of secondary malignancy in LFS patients treated with radiation therapy (RT); however, this risk is not well‐characteri...

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Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Hendrickson, Peter G., Luo, Yukun, Kohlmann, Wendy, Schiffman, Josh, Maese, Luke, Bishop, Andrew J., Lloyd, Shane, Kokeny, Kristine E., Hitchcock, Ying J., Poppe, Matthew M., Gaffney, David K., Tao, Randa
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Clinical Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643676/
https://ncbi.nlm.nih.gov/pubmed/32931654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3427
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