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Cost-effectiveness of early cancer surveillance for patients with Li–Fraumeni syndrome

INTRODUCTION: Patients with germline TP53 pathogenic variants (Li–Fraumeni syndrome [LFS]) are at extremely high lifetime risk of developing cancer. Recent data suggest that tumor surveillance for patients with LFS may improve survival through early cancer detection. The objective of this study was...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Tak, Casey R., Biltaji, Eman, Kohlmann, Wendy, Maese, Luke, Hainaut, Pierre, Villani, Anita, Malkin, David, Sherwin, Catherine M.T., Brixner, Diana I, Schiffman, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826253/
https://ncbi.nlm.nih.gov/pubmed/30719841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.27629
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