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Effect of 5-aza-2′-deoxycytidine on Estrogen Receptor Alpha/Beta and DNA Methyltransferase 1 Genes Expression, Apoptosis Induction, and Cell Growth Prevention of the Colon Cancer HT 29 Cell Line

BACKGROUND: Cellular activity such as gene expression is regulated by epigenetic mechanisms and modifications. In mammals, DNA methylation is an essential component of the epigenetic machinery of the cells. DNA hypermethylation of the several tumor suppressor genes (TSGs) is associated with transcri...

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Dades bibliogràfiques
Publicat a:Int J Prev Med
Autors principals: Sanaei, Masumeh, Kavoosi, Fraidoon
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer - Medknow 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643574/
https://ncbi.nlm.nih.gov/pubmed/33209217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijpvm.IJPVM_140_19
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