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Genistein and Trichostatin A Induction of Estrogen Receptor Alpha Gene Expression, Apoptosis and Cell Growth Inhibition in Hepatocellular Carcinoma HepG 2 Cells

Epigenetic changes such as DNA methylation and histone acetylation play important roles in determining gene expression. Hypermethylation of CpG islands of the promoter region of tumor suppressor genes can greatly influence carcinogenesis through transcriptional silencing. Acetylation of lysine in hi...

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Bibliografske podrobnosti
izdano v:Asian Pac J Cancer Prev
Main Authors: Sanaei, Masumeh, Kavoosi, Fraidoon, Salehi, Habibeh
Format: Artigo
Jezik:Inglês
Izdano: West Asia Organization for Cancer Prevention 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980908/
https://ncbi.nlm.nih.gov/pubmed/29286617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.12.3445
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