Coexistence of perseveration and apathy in the TDP-43(Q331K) knock-in mouse model of ALS–FTD

Perseveration and apathy are two of the most common behavioural and psychological symptoms of dementia (BPSDs) in amyotrophic lateral sclerosis–frontotemporal dementia (ALS–FTD). Availability of a validated and behaviourally characterised animal model is crucial for translational research into BPSD...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Kim, Eosu, White, Matthew A., Phillips, Benjamin U., Lopez-Cruz, Laura, Kim, Hyunjeong, Heath, Christopher J., Lee, Jong Eun, Saksida, Lisa M., Sreedharan, Jemeen, Bussey, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643138/
https://ncbi.nlm.nih.gov/pubmed/33149110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01078-9
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