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Discovery and Structural Analysis to Improve the Enantioselectivity of Hydroxynitrile Lyase from Parafontaria laminata Millipedes for (R)-2-Chloromandelonitrile Synthesis

[Image: see text] Hydroxynitrile lyase (HNL) catalyzes the reversible synthesis and degradation of cyanohydrins, which are important synthetic intermediates for fine chemical and pharmaceutical industries. Here, we report the discovery of HNL from Parafontaria laminata (PlamHNL) millipedes, purifica...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Nuylert, Aem, Nakabayashi, Makoto, Yamaguchi, Takuya, Asano, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643134/
https://ncbi.nlm.nih.gov/pubmed/33163773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03070
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