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Hydroxynitrile lyases from cyanogenic millipedes: molecular cloning, heterologous expression, and whole-cell biocatalysis for the production of (R)-mandelonitrile

Hydroxynitrile lyases (HNLs), which are key enzymes in cyanogenesis, catalyze the cleavage of cyanohydrins into carbonyl compounds and hydrogen cyanide. Since HNLs also catalyze the reverse reaction, they are used industrially for the asymmetric synthesis of cyanohydrins, which are valuable building...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamaguchi, Takuya, Nuylert, Aem, Ina, Atsutoshi, Tanabe, Tsutomu, Asano, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813103/
https://ncbi.nlm.nih.gov/pubmed/29445093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20190-x
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