Mycobacteria-Specific T Cells Are Generated in the Lung During Mucosal BCG Immunization or Infection With Mycobacterium tuberculosis

Specific T cell responses are central for protection against infection with M. tuberculosis. Here we show that mycobacteria-specific CD4 and CD8 T cells accumulated in the lung but not in the mediastinal lymph node (MLN) at different time points after M. tuberculosis infection or BCG immunization. P...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Basile, Juan I., Liu, Ruining, Mou, Wenjun, Gao, Yu, Carow, Berit, Rottenberg, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643023/
https://ncbi.nlm.nih.gov/pubmed/33193338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.566319
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