Peroxisomal Dysfunction Contributes to White Matter Injury Following Subarachnoid Hemorrhage in Rats via Thioredoxin-Interacting Protein-Dependent Manner

BACKGROUND AND PURPOSE: White matter injury (WMI) exists in the early stage of subarachnoid hemorrhage (SAH) and has not been well addressed so far. METHODS: We utilized short hairpin RNA (shRNA) and clustered regularly interspaced short palindromic repeats (CRISPR) to verify the role of peroxisomes...

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Publicat a:Front Cell Dev Biol
Autors principals: Xu, Weilin, Yan, Jun, Chen, Shuda, Ocak, Umut, Shao, Anwen, Zhang, Jianmin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642982/
https://ncbi.nlm.nih.gov/pubmed/33195210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.576482
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