C57BL/6 mice require a higher dose of cisplatin to induce renal fibrosis and CCL2 correlates with cisplatin-induced kidney injury

C57BL/6 mice are one of the most commonly used mouse strains in research, especially in kidney injury studies. However, C57BL/6 mice are resistant to chronic kidney disease-associated pathologies, particularly the development of glomerulosclerosis and interstitial fibrosis. Our laboratory and others...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Sears, Sophia M., Sharp, Cierra N., Krueger, Austin, Oropilla, Gabrielle B., Saforo, Douglas, Doll, Mark A., Megyesi, Judit, Beverly, Levi J., Siskind, Leah J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642885/
https://ncbi.nlm.nih.gov/pubmed/32830540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00196.2020
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