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Impaired renal hemodynamics and glomerular hyperfiltration contribute to hypertension-induced renal injury

Recently, we reported a mutation in γ-adducin (ADD3) was associated with an impaired myogenic response of the afferent arteriole and hypertension-induced chronic kidney disease (CKD) in fawn hooded hypertensive (FHH) rats. However, the mechanisms by which altered renal blood flow (RBF) autoregulatio...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Fan, Letao, Gao, Wenjun, Nguyen, Bond V., Jefferson, Joshua R., Liu, Yedan, Fan, Fan, Roman, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642882/
https://ncbi.nlm.nih.gov/pubmed/32830539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00239.2020
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