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Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase
Enzymes are catalysts of biological processes. Significant insight into their catalytic mechanisms has been obtained by relating site-directed mutagenesis studies to kinetic activity assays. However, revealing the detailed relationship between structural modifications and functional changes remains...
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| Veröffentlicht in: | IUCrJ |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7642793/ https://ncbi.nlm.nih.gov/pubmed/33209313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252520011008 |
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