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Zeb1 expression by tumor or stromal cells is associated with spatial distribution patterns of CD8+ tumor-infiltrating lymphocytes: a hypothesis-generating study on 113 triple negative breast cancers

Spatial organization of tumor microenvironment (TME) may influence tumor response to immunomodulatory therapies. Zeb1 is a driver of epithelial-mesenchymal transition, with several roles in immune cell development, however its role in shaping of the immune TME is not fully explored. We conducted a p...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Ouled Dhaou, Mona, Kossai, Myriam, Morel, Anne-Pierre, Devouassoux-Shisheboran, Mojgan, Puisieux, Alain, Penault-Llorca, Frederique, Radosevic-Robin, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642672/
https://ncbi.nlm.nih.gov/pubmed/33163276
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