CYP3A5 suppresses metastasis of lung adenocarcinoma through ATOH8/Smad1 axis

Cytochrome P450 3A5 (CYP3A5) maintains primary roles in toxic metabolism, catalyzes redox reaction, and contributes to chemotherapeutic resistance. However, the mechanism of CYP3A5 in carcinogenesis remains largely undefined. Here, we investigated a novel role of CYP3A5 inhibiting the metastasis in...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Mao, Qixing, Wang, Lin, Liang, Yingkuan, Dong, Gaochao, Xia, Wenjie, Hu, Jianzhong, Xu, Lin, Jiang, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642649/
https://ncbi.nlm.nih.gov/pubmed/33163265
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